Phentermine is a psycho-stimulant drug which has been used for treatment of obesity since many past years. Every prescription concerning weight loss contains the ingredient of phentermine in one brand or another. It is being utilized for weight loss in more than fifty per cent prescriptions owing to its low cost and more advantages. The history- of- phentermine goes back to 1959 when it was for the first time approved by FDA in the United States under the category of appetite suppressant for the purpose of curing obesity and its related diseases. In the same year phentermine resin was supplied to the drug stores for general sale. It became very popular with residents of the United States. Millions of people, who were worried about unwanted increase in their weight, used it successfully for the loss in their weight. Eleven years later in 1970 phentermine hydrochloride was developed. It was a variant of phentermine resin. History -of -phentermine indicates that this new form of phentermine was appreciated at even larger scale.
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The process of development of phentermine continued and its various refined forms came into drug markets with each passing year. Many pharmaceutical companies embarked upon the task of its preparation. For example Medeva Pharmaceuticals formulated lonamin and Gate Pharmaceuticals prepared Adipex. King Pharmaceuticals branded it as Fastin for the sake of SmithKline Beecham. In 1998 Fastin was stopped for company’s own reasons.
When we read the history- of –phentermine we come to know that it has been used in combined form with other drugs having the same purpose. During 1990s it was combined with Fenfluramine for the treatment of obesity. The experiment proved very fruitful and served the purpose without any notable side effects. It is also known as Phen-Fen. The first part of this combination symbolizes phentermine whereas the second part refers to Fenfluramine. Fenfluramine is a drug which is utilized for weight loss purposes and it was recognized by FDA in 1973. Although the combined form of Phen-Fen achieved the desired effects yet it couldn’t get approval by FDA. However, many doctors do prescribe this combination for treatment of obesity and weight loss.
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The research history-of-phentermine at the University of Rochester shows that for the determination of the efficacy of Phen-Fen several experiments were conducted. The person behind this research was Dr Michael Weintraub. He worked on it with a group of his colleagues. In 1992 he published a report in which he declared that combined form of Phen-Fen is more effective for treatment of obesity and weight problems. He opined that the use of Phen-Fen produced better results rather than losing weight through dieting and exercise. He also assured that its use has no notable side effects and patients can utilize it without any apprehension. After this declaration more and more people suffering from over-weight problems resorted to its use. Its popularity reached every nook and corner in the United States. According to statistics gathered in 1995 this drug was prescribed to more than 6.6 million people in America. However, later results showed that the drug Fenfluramine creates heart problems and in 1997 it was requested by FDA to stop its further use.
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FDA advised to retain the use of phentermine for the wider benefit of people who are obese and fat. Since then people suffering from weight problems and obesity are concentrating on the sole use of phentermine. The history -of -phentermine reveals that it is the best drug which can be used for treatment of diseases caused by over-weight and obesity. However, medical specialists are of the opinion that it should be prescribed by a competent doctor after a thorough medical examination of patients for safety and precautionary measures.